Sayburç is located on the southern foothills of the Eastern Taurus Mountains, on the threshold where the mountainous topography intersects with wide plains, on the plateau surrounding Harran Plain. The settlement is about 60 km east of the Euphrates River and 20 km southwest of downtown Şanlıurfa.
Sayburç, just like its other contemporaries in the Şanlıurfa plateau, takes place on limestone hills that are Eocene-origin (Pic. 1). The Neolithic settlement had been developed on two hills, one in the north which is relatively higher, and the other in south, low (Pic. 2). There is a third hill in the west, different from the other two with Roman quarries, caves, cisterns and no traces of Neolithic. The actual Roman settlement, however, had been established on the Neolithic fill in the north. Roman elements are also encountered on the hill in the northeast of the settlement.